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Vol 37(2021) N 6 p. 48-57; DOI 10.21519/0234-2758-2021-37-6-48-57
S.N. Marzanova1, D.A. Devrishov1, I.S. Turbina2, Ya.I. Alekseev3, N.V. Konovalova3, and N.S. Marzanov4*

Genetic Diagnostics of FANC1BY Mutation in Representatives of the Holstein Breed and Its Crosses

1K. I. Skryabin Moscow State Academy of Veterinary Medicine and Biotechnology, Ministry of Agriculture of the Russian Federation, Moscow, 109472, Russia
2Head Center for the Reproduction of Farm Animals, Ministry of Agriculture of the Russian Federation, Bykovo, Moscow Oblast, 142143, Russia
3Syntol, Moscow, 127550, Russia
4L.K. Ernst Federal Research Center for Animal Husbandry, Ministry of Education and Science of the Russian Federation, Dubrovitsy, Moscow Oblast, 142132, Russia

*nmarzanov@yandex.ru
Received - 04.07.2021; Accepted - 08.09.2021

REFERENCES

1. Marzanova S.N., Tokhov M.Kh., Marzanov N.S., et al. Genetic genealogy and assessment of bulls for carriage of CV and BL alleles. In: Materials of the International Scientific and Practical Conference "Increasing the Competitiveness of Livestock and the Tasks of Staffing," Bykovo, 2013, 19(1), 90-92 (in Russ.).

2. Marzanova S.N., Nagorniy V.A., Devrishov D.A., et al. Founder effect and genogeography of CV and BL mutations in black-and-white cattle. Russ. Agric. Sci., 2016, 42(1), 80-83. doi 10.3103/S1068367416010134

3. Ivanov V.A., Popov N.A., Marzanov N.S. Comparative analysis of the results of evaluating bulls using different methods. Problems of the biology of productive animals, 2016, 4, 69-80 (in Russ.).

4. ICAR Guidelines. 37th ICAR Biennial Session. Eds E. Skujina, E. Galvanoska, O. Leray, C. Mosconi, Riga (Latvia), 2010, 485 p. http://www.icar.org

5. Online Mendelian Inheritance in Animals. OMIA, 2014, 2021. http://omia.angis.org.au

6. VanRaden P.M., Olson K.M., Null D.J., Hutchison J.L. Harmful recessive effects on fertility detected by absence of homozygous haplotypes. J. Dairy Sci., 2011, 94, 6153-6161. doi 10.3168/jds.2011-4624

7. Casas E., Kehrli M.E.Jr. A Review of selected genes with known effects on performance and health of cattle. Front. Vet. Sci., 2016, 3, 113. doi 10.3389/fvets.2016.00113

8. Chun Hsuan Chao, Yi Ming Chen, Kuo Hua Lee. Genotype screening of bovine brachyspina in Taiwan Holstein cows. Am. J. Anim. Vet. Sci., 2020, 15(3), 206-210. doi 10.3844/ajavsp.2020.206.210

9. Agerholm J.S., Bendixen C., Arnbjerg J., Anderson O. Complex vertebral malformation in Holstein calves. J. Vet. Diagn. Invest., 2001, 13, 283-289. doi 10.1177/104063870101300401

10. Agerholm J.S., McEvoy F., Arnbjerg J. Brachyspina syndrome in a Holstein calf. J. Vet. Diagn. Invest., 2006, 18, 418-422. doi 10.1177/104063870601800421

11. Buck B.C., Ulrich R., Wöhlke A., et al. Missbildungen an der Wirbelsaule mit multiplen Organanomalien bei einem Kalb der Rasse Deutsche Holsteins (Vertebral and multiple organ malformations in a black and white German Holstein calf). Berl. Munch. Tierarztl. Wochenschr., 2010, 123, 251-255.

12. Georges M., Coppieters W., Charlier C., et al., inventors. A genetic marker test for brachyspina and fertility in cattle. Patent No. WO2010/012690 A1, Publ. 04.02.2010.

13. Charlier C., Agerholm J.S., Coppieters W., et al. A deletion in bovine FANCI gene compromises fertility by causing fetal death and brachyspina. PLoS One, 2012, 7(8), e43085. doi 10.1371/journal. pone.0043085

14. Agerholm J.S., DeLay J., Hicks B., Fredholm M. First confirmed case of the bovine brachyspina syndrome in Canada. Can. Vet. J., 2010, 51, 1349-1350.

15. Marzanova S.N. Development of Genodiagnostics of a Complex Vertebral Malformation [CVM] and Immunodeficiency [BLAD] in Animals of Black-and-White Holstein Cattle. PhD Thesis Biol. Sciences, Moscow, 2012, 144 p. (in Russ.).

16. Marzanova S.N., Devrishov D.A., Alekseev Ya.I., et al. Method for gene diagnosis of a mutant allele causing a short spine or brachispina in cattle, and a test system for implementation thereof. Patent RU 2664454 C2, Publ. 17.08.2018, bul. 23.

17. Zhivotovsky L.A. Population Biometrics. Nauka, Moscow, 1991, 276 p. (in Russ.).

18. Merkurieva E.K. Genetic Foundations of Selection in Cattle Breeding. Kolos, Moscow, 1977, 240 p. (in Russ.).

19. Testoni S., Diana A., Olzi E., Gentile A. Brachyspina syndrome in two Holstein calves. Vet. J., 2008, 177, 144-146. doi 10.1016/j.tvjl.2007.03.011

20. Marzanova S.N., Devrishov D.A., Alekseev Ya.I., et al. Diagnosis of immunodeficiencies and genetic abnormalities in productive animals. Study guide. Moscow, FGBOU VO MGAVMiB-MBA named after I. K.I. Scriabin, 2020, 132 p. (in Russ.). doi 10.18720/SPBPU/2/z20-20



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